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New Research Article | January 26, 2022

"Severely impaired CTL killing is a feature of the neurological disorder Niemann-Pick Syndrome type C1"


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An exciting collaboration of researchers including our own Dr. Ya Hui Hung and Prof. Mark Walterfang, have released a paper exploring the T- and killer-cell function in Niemann-Pick disease type C.

"Overall, our study revealed that NPC1 deficiency has a deleterious impact on CTL (but not natural killer cell) cytotoxicity that, in the long term, may predispose NP-C1 patients to atypical infections and impaired immune surveillance more generally."

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